3029240-84-1
3029240-84-1
Chemical Structure
D6808
- CAS No.: 3029240-84-1
- Formula:C30H25F3N6O2
- Molecular Weight:558.55
IUPAC Name: (14Z,52E)-63-(trifluoromethyl)-51,56-dihydro-11H-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-56,7-dione
InChIKey: PQNIGFMNUHDZKX-UHFFFAOYSA-N
SMILES: O=C1NCCCCN2C=C(C3=CN=C4C=CC(CCN5N=C(C6=CC(C(F)(F)F)=C1C=C6)C=CC5=O)=CC4=C3)C=N2
Biological Activity: D6808 is a highly selective and potent c‑Met inhibitor with an IC50 value of 2.9 nM. D6808 induces cell apoptosis and cell cycle arrest. D6808 can be used for the research of NSCLC and gastric cancers[1].
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D6808 | D6808 is a highly selective and potent c‑Met inhibitor with an IC50 value of 2.9 nM. D6808 induces cell apoptosis and cell cycle arrest. D6808 can be used for the research of NSCLC and gastric cancers. | |||||||||||||||||||||
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References
Keywords
