3029600-37-8
Chemical Structure
Enpp-1-IN-20
- CAS No.: 3029600-37-8
- Formula:C14H17N4O4P
- Molecular Weight:336.28
InChIKey: SQGOUGLKAOTADC-UIKWRGBMSA-N
SMILES: O=C1NC(N=CN=C2N3C[C@@]4([C@]([H])(C3)[C@H]4CCP(O)(O)=O)[H])=C2C=C1
Biological Activity: Enpp-1-IN-20 (Compound 31) is an ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor, with an IC50 of 0.09 nM. Enpp-1-IN-20 has strongest inhibitory activity in the cell-based assay, with an IC50 of 8.8 nM. Enpp-1-IN-20 has significant potency in both ENPP1 inhibition and STING pathway stimulation in vitro. Enpp-1-IN-20 can be used for the research of cancer[1].
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Enpp-1-IN-20 | 98.06% | Enpp-1-IN-20 (Compound 31) is an ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor, with an IC50 of 0.09 nM. Enpp-1-IN-20 has strongest inhibitory activity in the cell-based assay, with an IC50 of 8.8 nM. Enpp-1-IN-20 has significant potency in both ENPP1 inhibition and STING pathway stimulation in vitro. Enpp-1-IN-20 can be used for the research of cancer. | ||||||||||||||||||||
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Keywords