3031099-34-7

EGFR-IN-161 Chemical Structure
3031099-34-7

Chemical Structure

EGFR-IN-161

  • CAS No.: 3031099-34-7
  • Formula:C33H36Cl2N8O2
  • Molecular Weight:647.60

SMILES: COC1=CC(N(CCN(C)C)C)=C(C=C1NC2=NC(C3=CN(C4=C3C=CC=C4)CCCO)=CC=N2)/N=C/C5=C(C(Cl)=NC=C5)Cl

Biological Activity: EGFR-IN-161 (Compound DD-8) is a potent and reversible inhibitor of L858R/T790M/C797S mutant EGFR kinases, with an IC50 of 0.87 nM. EGFR-IN-161 can induce apoptosis process, G1-phase arrestation, and migration inhibition in tumor cells[1].

Cat. No. Product Name Purity Description Pricing
HY-172780 		EGFR-IN-161 EGFR-IN-161 (Compound DD-8) is a potent and reversible inhibitor of L858R/T790M/C797S mutant EGFR kinases, with an IC50 of 0.87 nM. EGFR-IN-161 can induce apoptosis process, G1-phase arrestation, and migration inhibition in tumor cells.
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