3031483-23-2
3031483-23-2
Chemical Structure
ThrRS-IN-3
- CAS. Nr.: 3031483-23-2
- Formula:C31H30Cl2N6O5
- Molecular Weight:637.51
IUPAC Name: (2S,3R)-2-amino-N-((R)-2-(3-(6,7-dichloro-4-oxoquinazolin-3(4H)-yl)propanamido)-1-(3-(1-oxoisoindolin-5-yl)phenyl)ethyl)-3-hydroxybutanamide
InChIKey: SXLUECWAPXFDGD-RKQBMHSKSA-N
SMILES: O=C(NC[C@@H](C1=CC(C2=CC(CN3)=C(C=C2)C3=O)=CC=C1)NC([C@@H](N)[C@@H](C)O)=O)CCN4C=NC5=C(C4=O)C=C(Cl)C(Cl)=C5
Biological Activity: ThrRS-IN-3 (compound 36j) is a highly potent threonyl-tRNA synthetase (ThrRS) inhibitor, with an IC50 value of 19 nM and a Kd of 34 nM for Salmonella enterica ThrRS. ThrRS-IN-3 has antibacterial activities[1].
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ThrRS-IN-3 | ThrRS-IN-3 (compound 36j) is a highly potent threonyl-tRNA synthetase (ThrRS) inhibitor, with an IC50 value of 19 nM and a Kd of 34 nM for Salmonella enterica ThrRS. ThrRS-IN-3 has antibacterial activities. | |||||||||||||||||||||
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