3031812-65-1

EGFR-IN-3 Chemical Structure
3031812-65-1

Chemical Structure

EGFR-IN-3

  • CAS No.: 3031812-65-1
  • Formula:C24H18F4N6O2S
  • Molecular Weight:530.50

IUPAC Name: 2-((2-((4-(3-fluorobenzamido)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylthiophene-3-carboxamide

InChIKey: MQLUFPGAAPEIPX-UHFFFAOYSA-N

SMILES: O=C(C1=C(NC2=NC(NC3=CC=C(NC(C4=CC=CC(F)=C4)=O)C=C3)=NC=C2C(F)(F)F)SC=C1)NC

Biological Activity: EGFR-IN-3 (Compound 4c) is a potent EGFR inhibitor with an IC50 of 0.32 µM against EGFRwt-TK. EGFR-IN-3 shows cytotoxic activity against cancer cell lines and induces apoptosis[1].

Cat. No. Product Name Purity Description Pricing
HY-144760 		EGFR-IN-3 EGFR-IN-3 (Compound 4c) is a potent EGFR inhibitor with an IC50 of 0.32 µM against EGFRwt-TK. EGFR-IN-3 shows cytotoxic activity against cancer cell lines and induces apoptosis.
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