3033951-64-0
3033951-64-0
Chemical Structure
ACI-19278
- CAS No.: 3033951-64-0
- Formula:C20H17F2N5OS
- Molecular Weight:413.44
InChIKey: NKXBUELDCAQJLQ-GFCCVEGCSA-N
SMILES: FC1=C(C2=NC(CCN(C3=CN=CC=C3)C4=O)=C4S2)C=CC(N5CC[C@@H](F)C5)=N1
Biological Activity: ACI-19278 is a TDP-43 PET tracer with an average Kd of 25 nM. ACI-19278 only binds to pathological TDP-43 aggregates and does not cross-react with Aβ, Tau, etc. [18F]ACI-19278 successfully visualized the TDP-43 pathology in the human brain through positron emission computed tomography. ACI-19278 can be used for in vivo diagnosis of TDP-43 protein lesions[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ACI-19278 | 99.45% | ACI-19278 is a TDP-43 PET tracer with an average Kd of 25 nM. ACI-19278 only binds to pathological TDP-43 aggregates and does not cross-react with Aβ, Tau, etc. [18F]ACI-19278 successfully visualized the TDP-43 pathology in the human brain through positron emission computed tomography. ACI-19278 can be used for in vivo diagnosis of TDP-43 protein lesions. | ||||||||||||||||||||
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