3036411-36-3
3036411-36-3
Chemical Structure
Mcl-1 inhibitor 16
- CAS No.: 3036411-36-3
- Formula:C25H29Cl2N3Pt
- Molecular Weight:637.51
InChIKey: BTJZYENDOPYKPT-UHFFFAOYSA-L
SMILES: Cl[Pt]1([N](C=CC2=C3N(CCCCCCCCC)C4=CC=CC=C24)=C3C5=CC=CC=[N]51)Cl
Biological Activity: Mcl-1 inhibitor 16 (Compound 9) is a mitochondrial targeting Platinum-based inhibitor of Mcl-1. Mcl-1 inhibitor 1 induces Bax/Bak-dependent apoptosis in cancer cells. Mcl-1 inhibitor 16 can be used alone or together with ABT-199 (HY-15531) and shows anti-tumor activity[1].
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Mcl-1 inhibitor 16 | Mcl-1 inhibitor 16 (Compound 9) is a mitochondrial targeting Platinum-based inhibitor of Mcl-1. Mcl-1 inhibitor 1 induces Bax/Bak-dependent apoptosis in cancer cells. Mcl-1 inhibitor 16 can be used alone or together with ABT-199 (HY-15531) and shows anti-tumor activity. | |||||||||||||||||||||
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