303776-85-4
303776-85-4
Chemical Structure
HCV-IN-50
- CAS No.: 303776-85-4
- Formula:C20H19N3O4S
- Molecular Weight:397.45
IUPAC Name: 3-(1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)-4-hydroxy-1-isobutylquinolin-2(1H)-one
InChIKey: VYPYSWWKHUDIRT-UHFFFAOYSA-N
SMILES: O=C1N(CC(C)C)C2=C(C=CC=C2)C(O)=C1C(NC3=CC=CC=C34)=NS4(=O)=O
Biological Activity: HCV-IN-50 (Compound 2) is a competitive and selective HCV NS5B RNA-dependent RNA polymerase inhibitor with an IC50 of 0.3 μM for NS5B △C21 enzyme over △C55 enzyme. HCV-IN-50 has an antiviral activity and efficiently blocks replication of HCV subgenomic replicons especially mutant replicons[1].
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HCV-IN-50 | HCV-IN-50 (Compound 2) is a competitive and selective HCV NS5B RNA-dependent RNA polymerase inhibitor with an IC50 of 0.3 μM for NS5B △C21 enzyme over △C55 enzyme. HCV-IN-50 has an antiviral activity and efficiently blocks replication of HCV subgenomic replicons especially mutant replicons. | |||||||||||||||||||||
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