3037967-71-5
3037967-71-5
Chemical Structure
IDH1 Inhibitor 9
- CAS No.: 3037967-71-5
- Formula:C26H30N4O3
- Molecular Weight:446.54
InChIKey: IWVDDNCSSVGRAH-UHFFFAOYSA-N
SMILES: OC1=CC(OC)=C(C/C=C(C)/C)C=C1C2=NC(N3CCNCC3)=NC(C4=CC=C(O)C=C4)=C2
Biological Activity: IDH1 Inhibitor 9 (compound 11S) is a potent IDH1 inhibitor with IC50 values of 124.4, 95.7 nM for IDH1 R132H, IDH1 R132C, respectively. IDH1 Inhibitor 9 induces apoptosis and cell cycle arrest at the S phase. IDH1 Inhibitor 9 shows anti-tumor activity[1].
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IDH1 Inhibitor 9 | IDH1 Inhibitor 9 (compound 11S) is a potent IDH1 inhibitor with IC50 values of 124.4, 95.7 nM for IDH1 R132H, IDH1 R132C, respectively. IDH1 Inhibitor 9 induces apoptosis and cell cycle arrest at the S phase. IDH1 Inhibitor 9 shows anti-tumor activity. | |||||||||||||||||||||
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