3039540-25-2
3039540-25-2
Chemical Structure
E3 Ligase Ligand-linker Conjugate 227
- CAS No.: 3039540-25-2
- Formula:C26H39N5O4
- Molecular Weight:485.62
InChIKey: SPBCRYPRUWNMQU-UHFFFAOYSA-N
SMILES: O=C(C(CC1)NC(C=C2)=CC=C2N3CCN(CC4CCN(C(OC(C)(C)C)=O)CC4)CC3)NC1=O
Biological Activity: E3 Ligase Ligand-Linker Conjugate 227 is an E3 ligase ligand-linker conjugate containing CRBN ligand-1 (HY-150799) and a linker (HY-W262798). E3 Ligase Ligand-linker Conjugate 227 can be linked to the target protein ligand BRD9 ligand-12 (HY-182084) to form a PROTAC molecule, XYD270 (HY-182082)[1].
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E3 Ligase Ligand-linker Conjugate 227 | E3 Ligase Ligand-Linker Conjugate 227 is an E3 ligase ligand-linker conjugate containing CRBN ligand-1 (HY-150799) and a linker (HY-W262798). E3 Ligase Ligand-linker Conjugate 227 can be linked to the target protein ligand BRD9 ligand-12 (HY-182084) to form a PROTAC molecule, XYD270 (HY-182082). | |||||||||||||||||||||
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