3043939-18-7
3043939-18-7
Chemical Structure
BI-9787
- CAS No.: 3043939-18-7
- Formula:C24H29F2N5O2S
- Molecular Weight:489.58
InChIKey: LPDOIXPRZOWBJV-HOCLYGCPSA-N
SMILES: CSC1=CC=C(C[C@@H](C(O)=O)C)C=C1NC2=C(C#N)C(C(F)F)=CC(N3CC[C@H](N(C)C)C3)=N2
Biological Activity: BI-9787 is a zwitterionic inhibitior for ketohexokinase, with an IC50 of 12 and 12.8 nM for hKHK-A and hKHK-C. BI-9787 exhibits good metabolic stability in rat hepatocyte and good pharmacokinetic characteristics in rats[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BI-9787 | 99.46% | BI-9787 is a zwitterionic inhibitior for ketohexokinase, with an IC50 of 12 and 12.8 nM for hKHK-A and hKHK-C. BI-9787 exhibits good metabolic stability in rat hepatocyte and good pharmacokinetic characteristics in rats. | ||||||||||||||||||||
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References
Keywords
