3053266-55-7
Chemical Structure
TBI
- CAS No.: 3053266-55-7
- Formula:C18H12F2N4O2S
- Molecular Weight:386.38
InChIKey: FFVXYOZVQLWDIF-NSIKDUERSA-N
SMILES: O=C(/C(NC1=S)=C/C2=CC(F)=C(C(F)=C2)O)N1CC3=C4C(N=CN4)=CC=C3
Biological Activity: TBI is a fluorescence enhancer with a Kd of 71 nM for the Broccoli fluorogenic RNA aptamer. TBI binds to the Broccoli fluorogenic RNA aptamer to activate its fluorescence.TBI undergoes photobleaching of its trans form, which dissociates rapidly, while cis-TBI from the media replaces the dissociated fluorophore to enable fluorophore recycling.TBI enables enhanced fluorescence of Broccoli during continuous cellular imaging (Ex/Em = 485/527 nm)[1].
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TBI | TBI is a fluorescence enhancer with a Kd of 71 nM for the Broccoli fluorogenic RNA aptamer. TBI binds to the Broccoli fluorogenic RNA aptamer to activate its fluorescence.TBI undergoes photobleaching of its trans form, which dissociates rapidly, while cis-TBI from the media replaces the dissociated fluorophore to enable fluorophore recycling.TBI enables enhanced fluorescence of Broccoli during continuous cellular imaging (Ex/Em = 485/527 nm). | |||||||||||||||||||||
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Keywords
