30557-81-4
30557-81-4
Chemical Structure
Bisabolangelone
- CAS No.: 30557-81-4
- Formula:C15H20O3
- Molecular Weight:248.32
IUPAC Name: (3R,3aR,7aS,Z)-3-hydroxy-3,6-dimethyl-2-(3-methylbut-2-en-1-ylidene)-3,3a,7,7a-tetrahydrobenzofuran-4(2H)-one
InChIKey: GNWNPLBSEQDDQV-VRBKASCLSA-N
SMILES: O=C1C=C(C)C[C@@]2([H])[C@]1([H])[C@@](C)(O)/C(O2)=C/C=C(C)\C
Biological Activity: Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bisabolangelone | 98.94% | Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities. | ||||||||||||||||||||
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References
- [1]. Jung HW, et al. Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells. Int Immunopharmacol. 2010 Feb;10(2):155-62. [Content Brief]
- [2]. Wang J, et al. The anti-ulcer activities of bisabolangelone from Angelica polymorpha. J Ethnopharmacol. 2009 Jun 22;123(2):343-6. [Content Brief]
