3056728-00-5
Chemical Structure
SOAT-IN-3
- CAS No.: 3056728-00-5
- Formula:C17H11Cl2N3O5S2
- Molecular Weight:472.32
InChIKey: WKEKKLGWLTZEHZ-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CC([N+]([O-])=O)=C1)(NC2=C(C(NC3=CC(Cl)=C(Cl)C=C3)=O)SC=C2)=O
Biological Activity: SOAT-IN-3 is a selective inhibitor of sodium-dependent organic anion transporter (SOAT/SLC10A6). SOAT-IN-3 reduces intracellular estradiol synthesis, the process of dehydroepiandrosterone (DHEA) production from DHEAS, and DHEAS-induced cancer cell proliferation. SOAT-IN-3 shows no cytotoxicity against breast cancer cells at the tested concentrations. SOAT-IN-3 can be used in the research of breast cancer[1].
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SOAT-IN-3 | SOAT-IN-3 is a selective inhibitor of sodium-dependent organic anion transporter (SOAT/SLC10A6). SOAT-IN-3 reduces intracellular estradiol synthesis, the process of dehydroepiandrosterone (DHEA) production from DHEAS, and DHEAS-induced cancer cell proliferation. SOAT-IN-3 shows no cytotoxicity against breast cancer cells at the tested concentrations. SOAT-IN-3 can be used in the research of breast cancer. | |||||||||||||||||||||
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Keywords
