3062073-94-0
3062073-94-0
Chemical Structure
MAT2A-IN-21
- CAS No.: 3062073-94-0
- Formula:C26H20F2N4O2
- Molecular Weight:458.46
SMILES: O=C1C(C2=CC3=C(C=C2)N=CN3C)=NC4=CC=C(C=C4N1C5=CC=C(C=C5)OC(F)F)C6CC6
Biological Activity: MAT2A-IN-21 (compound 28) is a potent methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 49 nM. MAT2A-IN-21 selectivity inhibits MTAP-deficient cancer cells[1].
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MAT2A-IN-21 | MAT2A-IN-21 (compound 28) is a potent methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 49 nM. MAT2A-IN-21 selectivity inhibits MTAP-deficient cancer cells. | |||||||||||||||||||||
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References
Keywords
