3067849-10-6
3067849-10-6
Chemical Structure
BJH-86
- CAS No.: 3067849-10-6
- Formula:C23H21N3O2
- Molecular Weight:371.43
InChIKey: TUDCOPHTWXSUSA-UHFFFAOYSA-N
SMILES: COC1=CC=C2N=CC=C(CC3=CC=CC(C4=CN(C5COC5)N=C4)=C3)C2=C1
Biological Activity: BJH-86 is a soluble mitochondrial complex 1 inhibitor (oxygen consumption rate inhibition IC50 = 5 μM). BJH-86 exhibits weak inhibitory activity against phosphodiesterase 10A (PDE10A) (IC50 >10 μM). BJH-86 can reduce cellular oxygen consumption and inhibit cancer cell proliferation. BJH-86 can be used for the research of cancer, such as lung cancer[1].
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BJH-86 | BJH-86 is a soluble mitochondrial complex 1 inhibitor (oxygen consumption rate inhibition IC50 = 5 μM). BJH-86 exhibits weak inhibitory activity against phosphodiesterase 10A (PDE10A) (IC50 >10 μM). BJH-86 can reduce cellular oxygen consumption and inhibit cancer cell proliferation. BJH-86 can be used for the research of cancer, such as lung cancer. | |||||||||||||||||||||
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