3081612-73-6

PROTAC DDR1 degrader-1 Chemical Structure
3081612-73-6

Chemical Structure

PROTAC DDR1 degrader-1

  • CAS No.: 3081612-73-6
  • Formula:C43H40F3N9O7
  • Molecular Weight:851.83

InChIKey: LRJVJOFWMOUJIW-UHFFFAOYSA-N

SMILES: COC1=CC=C(C=C1C#CC2=CN=C(N=C2)NC3CCN(CC3)CCC(NC4=CC=C5C(N(CC5=C4)C6CCC(NC6=O)=O)=O)=O)C(NC7=CC(C(N)=O)=CC(C(F)(F)F)=C7)=O

Biological Activity: PROTAC DDR1 degrader-1 is a potent and selective DDR1-targeting PROTAC degrader. PROTAC DDR1 degrader-1 selectively induces full-length DDR1 degradation via the ubiquitin proteasome system, blocking downstream signaling pathways. PROTAC DDR1 degrader-1 inhibits tumor cell migration and invasion. PROTAC DDR1 degrader-1 exhibits anti-tumor activity in mice. PROTAC DDR1 degrader-1 can be used for the research of DDR1-driven cancers[1].

Cat. No. Nom du produit Pureté Description Pricing
HY-176184
PROTAC DDR1 degrader-1 98.69% PROTAC DDR1 degrader-1 is a potent and selective DDR1-targeting PROTAC degrader. PROTAC DDR1 degrader-1 selectively induces full-length DDR1 degradation via the ubiquitin proteasome system, blocking downstream signaling pathways. PROTAC DDR1 degrader-1 inhibits tumor cell migration and invasion. PROTAC DDR1 degrader-1 exhibits anti-tumor activity in mice. PROTAC DDR1 degrader-1 can be used for the research of DDR1-driven cancers.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References