3096376-30-3
3096376-30-3
Chemical Structure
Menin-MLL inhibitor 34
- CAS No.: 3096376-30-3
- Formula:C40H54FN9O4S
- Molecular Weight:775.98
InChIKey: IXQZOWVBGXCSCW-CMDGGOBGSA-N
SMILES: O=C(N(CC)C(C)C)C1=CC(F)=CC=C1NC2=CN=CN=C2N3CCN(CC4CN(C5=CC=C(S(=O)(C6CN(C(/C=C/CN(C)C)=O)C6)=O)C=C5)C4)C(C)C3
Biological Activity: Menin-MLL inhibitor 34 (Compound 37) is a selective and potent Menin-MLL inhibitor, with an IC50 of 18.21 nM for Menin. Menin-MLL inhibitor 34 has long-lasting anti-leukemic effects by reducing Menin protein levels and down-regulating MEN1 transcription[1].
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Menin-MLL inhibitor 34 | Menin-MLL inhibitor 34 (Compound 37) is a selective and potent Menin-MLL inhibitor, with an IC50 of 18.21 nM for Menin. Menin-MLL inhibitor 34 has long-lasting anti-leukemic effects by reducing Menin protein levels and down-regulating MEN1 transcription. | |||||||||||||||||||||
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