3096805-79-4
3096805-79-4
Chemical Structure
AS-254s
- CAS No.: 3096805-79-4
- Formula:C36H41ClN6O3S2
- Molecular Weight:705.33
InChIKey: BPGCWHKAMJXFNM-UHFFFAOYSA-N
SMILES: ClC1=C(C2=CC=C1CNC(C3CC4(C3)CCN(CC4)CCNC(C5=NC=CS5)=O)=O)N(C=C2C6=CC(C(N)=S)=CC=C6)C7CCOCC7
Biological Activity: AS-254s is the inhibitor for absent, small, or homeotic-like 1 protein (ASH1L) with an IC50 of 94 nM (FP assay). AS-254s exhibits antiproliferative activity against MLL1-rearranged leukemic cells with GI50 <1 μM. AS-254s induces the differentiation of MLL1-r leukemic cell[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AS-254s | 98.96% | AS-254s is the inhibitor for absent, small, or homeotic-like 1 protein (ASH1L) with an IC50 of 94 nM (FP assay). AS-254s exhibits antiproliferative activity against MLL1-rearranged leukemic cells with GI50 <1 μM. AS-254s induces the differentiation of MLL1-r leukemic cell. | ||||||||||||||||||||
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References
Keywords
