3097194-50-5
3097194-50-5
Chemical Structure
TGF-β1/Smad-IN-1
- CAS No.: 3097194-50-5
- Formula:C18H19ClN2O6
- Molecular Weight:394.81
InChIKey: GLZXPSRJBCEEPY-WBAAUIMVSA-N
SMILES: ClC(C=C1NCC2=CC[C@@]3([H])[C@]2([H])[C@H](OC)OC=C3C(OC)=O)=C(C=C1)[N+]([O-])=O
Biological Activity: TGF-β1/Smad-IN-1 (compound C9) is a potent TGF-β1/Smad inhibitor. TGF-β1/Smad-IN-1 inhibits the expression of fibrosis markers (α-SMA and COL1A1) induced by TGF-β1. TGF-β1/Smad-IN-1 shows antifibrotic effects. TGF-β1/Smad-IN-1 has the potential for the research of hepatic fibrosis[1].
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TGF-β1/Smad-IN-1 | TGF-β1/Smad-IN-1 (compound C9) is a potent TGF-β1/Smad inhibitor. TGF-β1/Smad-IN-1 inhibits the expression of fibrosis markers (α-SMA and COL1A1) induced by TGF-β1. TGF-β1/Smad-IN-1 shows antifibrotic effects. TGF-β1/Smad-IN-1 has the potential for the research of hepatic fibrosis. | |||||||||||||||||||||
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