3098827-88-1

NLRP3-IN-60 Chemical Structure
3098827-88-1

Chemical Structure

NLRP3-IN-60

  • CAS No.: 3098827-88-1
  • Formula:C23H24F2N4O4S
  • Molecular Weight:490.52

InChIKey: ITMGDDOSMDGHTK-UHFFFAOYSA-N

SMILES: FC1=NN2C=C1S(=O)(NC(CC3=C(C4=CC(OCC2(C)C)=NC=C4)C=CC(F)=C3C(C)C)=O)=O

Biological Activity: NLRP3-IN-60 (Compound 39) is the orally active inhibitor for NLRP3. NLRP3-IN-60 inhibits pyroptosis with an IC50 of 13 nM in THP-1 cell. NLRP3-IN-60 inhibits IL-1β release with an IC50 of 225 nM in human whole blood[1].

Cat. No. Product Name Purity Description Pricing
HY-170364 		NLRP3-IN-60 NLRP3-IN-60 (Compound 39) is the orally active inhibitor for NLRP3. NLRP3-IN-60 inhibits pyroptosis with an IC50 of 13 nM in THP-1 cell. NLRP3-IN-60 inhibits IL-1β release with an IC50 of 225 nM in human whole blood.
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