3105041-48-0
3105041-48-0
Chemical Structure
AVI-4206
- CAS No.: 3105041-48-0
- Formula:C19H23N7O2
- Molecular Weight:381.43
IUPAC Name: 1-(4-((2,2-dimethyl-5-oxopyrrolidin-1-yl)amino)-9H-pyrimido[4,5-b]indol-8-yl)-3-ethylurea
InChIKey: HBWCYQWGCNBURO-UHFFFAOYSA-N
SMILES: O=C(NCC)NC1=CC=CC2=C1NC3=NC=NC(NN4C(C)(C)CCC4=O)=C32
Biological Activity: AVI-4206 is a selective Mac1 inhibitor with an lC50 of 64 nM. AVI-4206 reduces viral replication, restores an interferon response, and leads to a survival benefit in an animal model of SARS-CoV-2 infection. AVI-4206 can be used the study of SARS-CoV-2 infection[1].
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AVI-4206 | AVI-4206 is a selective Mac1 inhibitor with an lC50 of 64 nM. AVI-4206 reduces viral replication, restores an interferon response, and leads to a survival benefit in an animal model of SARS-CoV-2 infection. AVI-4206 can be used the study of SARS-CoV-2 infection. | |||||||||||||||||||||
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References
Keywords
