3109024-27-0

POLQ-IN-1 Chemical Structure
3109024-27-0

Chemical Structure

POLQ-IN-1

  • CAS No.: 3109024-27-0
  • Formula:C28H26ClF3N4O5
  • Molecular Weight:590.98

InChIKey: SHTJJJIRVCGLME-UHFFFAOYSA-N

SMILES: O=C(C(CCOC1=CC(Cl)=C(C2=NC3=C(N2CC4=CC(OC(F)(F)F)=CC=C4)N=CN=C3OC5(CC5)C)C=C1)C)O

Biological Activity: POLQ-IN-1 is a DNA polymerase θ (POLQ) inhibitor with a pIC50 of 8.2. POLQ-IN-1 inhibits the proliferation of homologous recombination-deficient cells. POLQ-IN-1 is used for the research of homologous recombination-deficient tumors[1].

Cat. No. Product Name Purity Description Pricing
HY-182322
POLQ-IN-1 POLQ-IN-1 is a DNA polymerase θ (POLQ) inhibitor with a pIC50 of 8.2. POLQ-IN-1 inhibits the proliferation of homologous recombination-deficient cells. POLQ-IN-1 is used for the research of homologous recombination-deficient tumors.
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