3109024-27-0
Chemical Structure
POLQ-IN-1
- CAS No.: 3109024-27-0
- Formula:C28H26ClF3N4O5
- Molecular Weight:590.98
InChIKey: SHTJJJIRVCGLME-UHFFFAOYSA-N
SMILES: O=C(C(CCOC1=CC(Cl)=C(C2=NC3=C(N2CC4=CC(OC(F)(F)F)=CC=C4)N=CN=C3OC5(CC5)C)C=C1)C)O
Biological Activity: POLQ-IN-1 is a DNA polymerase θ (POLQ) inhibitor with a pIC50 of 8.2. POLQ-IN-1 inhibits the proliferation of homologous recombination-deficient cells. POLQ-IN-1 is used for the research of homologous recombination-deficient tumors[1].
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POLQ-IN-1 | POLQ-IN-1 is a DNA polymerase θ (POLQ) inhibitor with a pIC50 of 8.2. POLQ-IN-1 inhibits the proliferation of homologous recombination-deficient cells. POLQ-IN-1 is used for the research of homologous recombination-deficient tumors. | |||||||||||||||||||||
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Keywords