3109265-41-7
Chemical Structure
MYC-IN-4
- CAS No.: 3109265-41-7
- Formula:C19H10F6N2O2
- Molecular Weight:412.29
IUPAC Name: 3-(trifluoromethyl)-5-(2-(4-(trifluoromethyl)phenyl)benzofuran-5-yl)-1H-pyrazole
InChIKey: VKIQUTANQGKKNL-UHFFFAOYSA-N
SMILES: OC1=C2C(OC(C3=CC=C(C=C3)C(F)(F)F)=C2)=CC=C1C4=CC(C(F)(F)F)=NN4
Biological Activity: MYC-IN-4 is a MYC inhibitor. MYC-IN-4 impairs MYC/MAX protein-protein interaction (IC50 = 3.06 μM). MYC-IN-4 inhibits MYC-aberrant PC-3 prostate cancer cells with an IC50 of 0.440 μM. MYC-IN-4 demonstrates potent antitumor efficacy in FVB mice bearing Myc-CaP prostate tumor allografts. MYC-IN-4 can be used for the study of prostate cancer[1].
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MYC-IN-4 | MYC-IN-4 is a MYC inhibitor. MYC-IN-4 impairs MYC/MAX protein-protein interaction (IC50 = 3.06 μM). MYC-IN-4 inhibits MYC-aberrant PC-3 prostate cancer cells with an IC50 of 0.440 μM. MYC-IN-4 demonstrates potent antitumor efficacy in FVB mice bearing Myc-CaP prostate tumor allografts. MYC-IN-4 can be used for the study of prostate cancer. | |||||||||||||||||||||
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Keywords
