321351-81-9

[D-Trp8]-γ-MSH Chemical Structure
321351-81-9

Chemical Structure

[D-Trp8]-γ-MSH

  • CAS No.: 321351-81-9
  • Formula:C74H99N21O16S
  • Molecular Weight:1570.77

IUPAC Name: (5S,8S,11S,14R,17S,20S,23S,29S,32S,35S)-23-((1H-imidazol-5-yl)methyl)-14-((1H-indol-3-yl)methyl)-35-amino-5,20-dibenzyl-11-(carboxymethyl)-8,17-bis(3-guanidinopropyl)-36-(4-hydroxyphenyl)-32-isopropyl-29-(2-(methylthio)ethyl)-4,7,10,13,16,19,22,25,28,31,3

InChIKey: GZWUQPQBOGLSIM-MDMVXOTPSA-N

SMILES: OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(NCC(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O

Biological Activity: [D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis[1][2].

Cat. No. Product Name Purity Description Pricing
HY-P1217 		[D-Trp8]-γ-MSH 98.25% [D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References

Keywords