321351-81-9

[D-Trp8]-γ-MSH Chemical Structure
321351-81-9

Chemical Structure

[D-Trp8]-γ-MSH

  • CAS No.: 321351-81-9
  • Formula:C74H99N21O16S
  • Molecular Weight:1570.77

IUPAC Name: (5S,8S,11S,14R,17S,20S,23S,29S,32S,35S)-23-((1H-imidazol-5-yl)methyl)-14-((1H-indol-3-yl)methyl)-35-amino-5,20-dibenzyl-11-(carboxymethyl)-8,17-bis(3-guanidinopropyl)-36-(4-hydroxyphenyl)-32-isopropyl-29-(2-(methylthio)ethyl)-4,7,10,13,16,19,22,25,28,31,3

InChIKey: GZWUQPQBOGLSIM-MDMVXOTPSA-N

SMILES: OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(NCC(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O

Biological Activity: [D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis[1][2].

Cat. No. Product Name Purity Description Pricing
HY-P1217 		[D-Trp8]-γ-MSH 98.25% [D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis.
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)

Amount:

USD 0.00

This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

Pricing 
Expand Hide
References

Keywords