339986-90-2
Chemical Structure
Tucotuzumab celmoleukin
Synonym(s): EMD 273066; huKS-IL2
- CAS No.: 339986-90-2
- Formula:N/A
- Molecular Weight:(175.114 kDa)
SMILES: [Tucotuzumab celmoleukin]
Biological Activity: Tucotuzumab celmoleukin (EMD 273066) is an immunocytokine. Tucotuzumab celmoleukin consists of the following components: an IgG1 monoclonal antibody targeting human EpCAM antigen, and two molecules of IL2. Tucotuzumab celmoleukin binds to EpCAM. Tucotuzumab celmoleukin exerts anti-tumor effects on colon adenocarcinoma in synergy with radiofrequency ablation. Tucotuzumab celmoleukin can be used in research related to colon adenocarcinoma and colon cancer[1][2].
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Tucotuzumab celmoleukin | 98.797% | Tucotuzumab celmoleukin (EMD 273066) is an immunocytokine. Tucotuzumab celmoleukin consists of the following components: an IgG1 monoclonal antibody targeting human EpCAM antigen, and two molecules of IL2. Tucotuzumab celmoleukin binds to EpCAM. Tucotuzumab celmoleukin exerts anti-tumor effects on colon adenocarcinoma in synergy with radiofrequency ablation. Tucotuzumab celmoleukin can be used in research related to colon adenocarcinoma and colon cancer. | ||||||||||||||||||||
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- [1]. Johnson EE, et al. Radiofrequency ablation combined with KS-IL2 immunocytokine (EMD 273066) results in an enhanced antitumor effect against murine colon adenocarcinoma. Clin Cancer Res. 2009;15(15):4875-4884. [Content Brief]
- [2]. Wang Z, et al. High-Affinity Fully Human Anti-EpCAM Antibody with Biased IL-2 Exhibits Potent Antitumor Activity. Biomolecules. 2024;14(11):1399. Published 2024 Nov 2. [Content Brief]
Keywords
