34118-92-8
34118-92-8
Chemical Structure
N-Acetylprocainamide hydrochloride
Synonym(s): Acecainide hydrochloride; NAPA hydrochloride
- CAS No.: 34118-92-8
- Formula:C15H24ClN3O2
- Molecular Weight:313.82
IUPAC Name: 4-acetamido-N-(2-(diethylamino)ethyl)benzamide hydrochloride
InChIKey: IYEWBJUCJHKLHD-UHFFFAOYSA-N
SMILES: O=C(NCCN(CC)CC)C1=CC=C(NC(C)=O)C=C1.Cl
Biological Activity: N-Acetylprocainamide (Acecainide) hydrochloride is a class III antiarrhythmic, which blocks K+ channels. N-Acetylprocainamide hydrochloride exerts inhibitory effects on the maximum following frequency (MFF) of isolated rabbit atria. N-Acetylprocainamide hydrochloride can be used for the study of arrhythmias[1][2][3].
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N-Acetylprocainamide hydrochloride | 99.83% | N-Acetylprocainamide (Acecainide) hydrochloride is a class III antiarrhythmic, which blocks K+ channels. N-Acetylprocainamide hydrochloride exerts inhibitory effects on the maximum following frequency (MFF) of isolated rabbit atria. N-Acetylprocainamide hydrochloride can be used for the study of arrhythmias. | ||||||||||||||||||||
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N-Acetylprocainamide hydrochloride (Standard) | ≥98% | N-Acetylprocainamide (Acecainide) hydrochloride (Standard) is the analytical standard of N-Acetylprocainamide hydrochloride (HY-101433). This product is intended for research and analytical applications. N-Acetylprocainamide hydrochloride is a class III antiarrhythmic, which blocks K+ channels. N-Acetylprocainamide hydrochloride exerts inhibitory effects on the maximum following frequency (MFF) of isolated rabbit atria. N-Acetylprocainamide hydrochloride can be used for the study of arrhythmias. | ||||||||||||||||||||
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References
- [1]. Minchin RF, et al. Antiarrhythmic potency of procainamide and N-acetylprocainamide in rabbits. Eur J Pharmacol. 1978 Jan 1;47(1):51-6. [Content Brief]
- [2]. Nakahara T, et al. Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle. Eur J Pharmacol. 2001 Mar 9;415(1):73-8. [Content Brief]
- [3]. Okumura K, et al. Effects of N-acetylprocainamide on experimental atrial flutter and atrial electrophysiologic properties in conscious dogs with sterile pericarditis: comparison with the effects of quinidine. J Am Coll Cardiol. 1987 Jun;9(6):1332-8. [Content Brief]
