34168-56-4
34168-56-4
Chemical Structure
Catalponol
- CAS No.: 34168-56-4
- Formula:C15H18O2
- Molecular Weight:230.30
IUPAC Name: (2R,4S)-4-hydroxy-2-(3-methylbut-2-en-1-yl)-3,4-dihydronaphthalen-1(2H)-one
InChIKey: BTQXIESSQVRLCV-RISCZKNCSA-N
SMILES: O=C1C2=CC=CC=C2[C@@H](O)C[C@H]1C/C=C(C)/C
Biological Activity: Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells[1][2].
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Catalponol | Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells. | |||||||||||||||||||||
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References
- [1]. Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75. [Content Brief]
- [2]. Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. [Content Brief]
