347840-08-8
347840-08-8
Chemical Structure
2-Methylsuccinic acid-d6
- CAS No.: 347840-08-8
- Formula:C5H2D6O4
- Molecular Weight:138.15
IUPAC Name: 2-(methyl-d3)succinic-2,3,3-d3 acid
InChIKey: WXUAQHNMJWJLTG-LIDOUZCJSA-N
SMILES: OC(C([2H])([2H])C(C([2H])([2H])[2H])([2H])C(O)=O)=O
Biological Activity: 2-Methylsuccinic acid-d6 is the deuterium labeled 2-Methylsuccinic acid[1]. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy[2][3].
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2-Methylsuccinic acid-d6 | 2-Methylsuccinic acid-d6 is the deuterium labeled 2-Methylsuccinic acid. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. | |||||||||||||||||||||
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2-Methylsuccinic acid (Standard) | 99.90% | 2-Methylsuccinic acid (Standard) is the analytical standard of 2-Methylsuccinic acid. This product is intended for research and analytical applications. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. | ||||||||||||||||||||
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2-Methylsuccinic acid | 98.0% | 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Grosso S, et al. Ethylmalonic encephalopathy: further clinical and neuroradiological characterization. J Neurol. 2002 Oct;249(10):1446-50. [Content Brief]
- [3]. Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul47(7):836-9. [Content Brief]
