36531-26-7
36531-26-7
Chemical Structure
Oxantel
Synonym(s): CP-14445
- CAS No.: 36531-26-7
- Formula:C13H16N2O
- Molecular Weight:216.28
IUPAC Name: (E)-3-(2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)vinyl)phenol
InChIKey: VRYKTHBAWRESFI-VOTSOKGWSA-N
SMILES: OC1=CC=CC(/C=C/C2=NCCCN2C)=C1
Biological Activity: Oxantel (CP-14445) is an anthelmintic agent that potently against Trichuris muris. Oxantel inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM)[1][2].
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Oxantel | Oxantel (CP-14445) is an anthelmintic agent that potently against Trichuris muris. Oxantel inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM). | |||||||||||||||||||||
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References
- [1]. Richard J Martin, et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. Int J Parasitol. 2004 Aug;34(9):1083-90. [Content Brief]
- [2]. Dashper S, et al. Oxantel disrupts polymicrobial biofilm development of periodontal pathogens. Antimicrob Agents Chemother. 2014;58(1):378-85. [Content Brief]
Keywords
