368451-07-4
368451-07-4
Chemical Structure
6-Hydroxy bexarotene
- CAS No.: 368451-07-4
- Formula:C24H28O3
- Molecular Weight:364.48
IUPAC Name: 4-(1-(6-hydroxy-3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid
InChIKey: WTWGVKDCAJSUBZ-UHFFFAOYSA-N
SMILES: CC1=CC2=C(C(C)(CC(C2(C)C)O)C)C=C1C(C3=CC=C(C=C3)C(O)=O)=C
Biological Activity: 6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors[1].
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6-Hydroxy bexarotene | 6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors. | |||||||||||||||||||||
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