372-97-4
Chemical Structure
Farnesyl pyrophosphate
Synonym(s): Farnesyl diphosphate
- CAS No.: 372-97-4
- Formula:C15H28O7P2
- Molecular Weight:382.33
IUPAC Name: (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate
InChIKey: VWFJDQUYCIWHTN-YFVJMOTDSA-N
SMILES: O=P(O)(O)OP(OC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)(O)=O
Biological Activity: Farnesyl pyrophosphate is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.
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Farnesyl pyrophosphate | Farnesyl pyrophosphate is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases. | |||||||||||||||||||||
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Keywords