37731-67-2
37731-67-2
Chemical Structure
3’-Deoxy-3’-α-C-methyl-5-fluorouridine
- CAS No.: 37731-67-2
- Formula:C10H13FN2O5
- Molecular Weight:260.22
IUPAC Name: 5-fluoro-1-((2R,3R,4S,5S)-3-hydroxy-5-(hydroxymethyl)-4-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: MPBZJBJXCOVBCK-FJGDRVTGSA-N
SMILES: OC[C@@H]1[C@@H](C)[C@@H](O)[C@H](N2C(NC(C(F)=C2)=O)=O)O1
Biological Activity: 3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-Deoxy-3’-α-C-methyl-5-fluorouridine | 3’-Deoxy-3’-α-C-methyl-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
