3881-21-8
Chemical Structure
2'-O-Methylinosine
- CAS No.: 3881-21-8
- Formula:C11H14N4O5
- Molecular Weight:282.26
IUPAC Name: 9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: HPHXOIULGYVAKW-IOSLPCCCSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N2C(N=CNC3=O)=C3N=C2)O1
Biological Activity: 2'-O-Methylinosine is a derivative of 2'-O-Methyladenosine. 2'-O-Methylinosine can be formed by chemical deamination of unmethylated 2'-O-Methyladenosine (HY-W011552). 2'-O-Methylinosine does not induce spore germination in Bacillus cereus. 2'-O-Methylinosine can be used in studies on diabetic nephropathy and HIV infection[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2'-O-Methylinosine | 99.27% | 2'-O-Methylinosine is a derivative of 2'-O-Methyladenosine. 2'-O-Methylinosine can be formed by chemical deamination of unmethylated 2'-O-Methyladenosine (HY-W011552). 2'-O-Methylinosine does not induce spore germination in Bacillus cereus. 2'-O-Methylinosine can be used in studies on diabetic nephropathy and HIV infection. | ||||||||||||||||||||
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References
- [1]. Liu S, et al. Reversible m6Am methylation of snRNA by FTO controls morphine reward and tolerance without altering analgesia. bioRxiv. 2026:2026-08.
- [2]. Valdés A, et al. Comprehensive metabolomic study of the response of HK-2 cells to hyperglycemic hypoxic diabetic-like milieu. Scientific reports. 2021 Mar 03;11(1):5058.
- [3]. Abel-Santos E, et al. Differential nucleoside recognition during Bacillus cereus 569 (ATCC 10876) spore germination. New Journal of Chemistry. 2007 May 10;31(5):748-55.
- [4]. Behm-Ansmant I, et al. Use of specific chemical reagents for detection of modified nucleotides in RNA. Journal of nucleic acids. 2011;2011(1):408053.
- [5]. Hyde RM. “Senseless” nucleic acid macromolecules: Synthesis, et al. The University of Utah; 2002.
- [6]. Hyde RM, et al. Antiviral amphipathic oligo- and polyribonucleotides: analogue development and biological studies. Journal of medicinal chemistry. 2003 May 08;46(10):1878-85. [Content Brief]
