439579-24-5
Chemical Structure
3’-Deoxy-3’-fluoro-2-thiouridine
- CAS No.: 439579-24-5
- Formula:C9H11FN2O4S
- Molecular Weight:262.26
IUPAC Name: 1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: IOIXFCHUVNXRSU-XVFCMESISA-N
SMILES: F[C@H]1[C@@H](O)[C@H](N(C(N2)=S)C=CC2=O)O[C@@H]1CO
Biological Activity: 3’-Deoxy-3’-fluoro-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-Deoxy-3’-fluoro-2-thiouridine | 3’-Deoxy-3’-fluoro-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
