4433-40-3
Chemical Structure
5-Hydroxymethyluracil
- CAS No.: 4433-40-3
- Formula:C5H6N2O3
- Molecular Weight:142.11
IUPAC Name: 5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione
InChIKey: JDBGXEHEIRGOBU-UHFFFAOYSA-N
SMILES: O=C1NC(C(CO)=CN1)=O
Biological Activity: 5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-Hydroxymethyluracil | 99.85% | 5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase. | ||||||||||||||||||||
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5-Hydroxymethyluracil (Standard) | ≥98% | 5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase. | ||||||||||||||||||||
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5-Hydroxymethyluracil-d3 | 99% | 5-Hydroxymethyluracil-d3 is the deuterium labeled 5-Hydroxymethyluracil. 5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase. | ||||||||||||||||||||
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2,4-Dihydroxypyrimidine-5-carboxylic Acid | 99.90% | 2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) is a linker. 2,4-Dihydroxypyrimidine-5-carboxylic acid can be assembled with various metal ions. 2,4-Dihydroxypyrimidine-5-carboxylic acid can be enzymatically converted to Uracil (HY-I0960). | ||||||||||||||||||||
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5-Fluorouracil-13C,15N2 | 5-Fluorouracil-13C,15N2 is the 13C and 15N labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. | |||||||||||||||||||||
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5-Fluorouracil-13C4,15N2 | 5-Fluorouracil-13C4,15N2 is the 13C and 15N labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV. | |||||||||||||||||||||
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5-Chlorouracil (Standard) | 99.05% | 5-Chlorouracil (Standard) is the analytical standard of 5-Chlorouracil. This product is intended for research and analytical applications. 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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5-Bromouracil | 99.99% | 5-Bromouracil is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Thymine | 99.94% | Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase (DPD), with a Km value of 2.2 μM, Ki of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg. | ||||||||||||||||||||
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Thymine-15N2 | Thymine-15N2 is the 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-13C | Thymine-13C is the 13C labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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Thymine-13C5,15N,15N2 | Thymine-13C5,15N2 (5-Methyluacil-13C5,15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. | |||||||||||||||||||||
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5-Formyluracil | 97.89% | 5-Formyluracil (Uracil-5-carboxaldehyde) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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