473921-12-9

Lersivirine Chemical Structure
473921-12-9

Chemical Structure

Lersivirine

Synonym(s): UK-453061

  • CAS No.: 473921-12-9
  • Formula:C17H18N4O2
  • Molecular Weight:310.35

IUPAC Name: 5-((3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl)oxy)isophthalonitrile

InChIKey: MCPUZZJBAHRIPO-UHFFFAOYSA-N

SMILES: CCC1=NN(CCO)C(CC)=C1OC2=CC(C#N)=CC(C#N)=C2

Biological Activity: Lersivirine (UK-453061) is potent and selective non-nucleoside reverse transcription inhibitor (NNRTI; IC50=119 nM) with excellent efficacy against NNRTI-resistant viruses. Lersivirine exhibits potent antiretroviral activity against wild-type HIV virus and clinically relevant NNRTI-resistant strains[1].

Cat. No. Product Name Purity Description Pricing
HY-14267
Lersivirine 98.36% Lersivirine (UK-453061) is potent and selective non-nucleoside reverse transcription inhibitor (NNRTI; IC50=119 nM) with excellent efficacy against NNRTI-resistant viruses. Lersivirine exhibits potent antiretroviral activity against wild-type HIV virus and clinically relevant NNRTI-resistant strains.
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