4857-06-1
4857-06-1
Chemical Structure
2-Chlorobenzimidazole
- CAS No.: 4857-06-1
- Formula:C7H5ClN2
- Molecular Weight:152.58
IUPAC Name: 2-chloro-1H-benzo[d]imidazole
InChIKey: AYPSHJCKSDNETA-UHFFFAOYSA-N
SMILES: ClC1=NC2=CC=CC=C2N1
Biological Activity: 2-Chlorobenzimidazole is a pharmaceutical intermediate used in the synthesis of a series of derivatives with anti-human cytomegalovirus (HCMV) activity. 2-Chlorobenzimidazole can be used to form metal complexes (cobalt, copper, and zinc), with zinc complexes exhibiting significant anticancer activity[1][2].
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2-Chlorobenzimidazole | 98.0% | 2-Chlorobenzimidazole is a pharmaceutical intermediate used in the synthesis of a series of derivatives with anti-human cytomegalovirus (HCMV) activity. 2-Chlorobenzimidazole can be used to form metal complexes (cobalt, copper, and zinc), with zinc complexes exhibiting significant anticancer activity. | ||||||||||||||||||||
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References
- [1]. Zou R, Drach JC, Townsend LB. Design, synthesis, and antiviral evaluation of 2-chloro-5,6-dihalo-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections. J Med Chem. 1997 Feb 28;40(5):811-8. [Content Brief]
- [2]. Sánchez-Guadarrama O, et al. Cytotoxic activity, X-ray crystal structures and spectroscopic characterization of cobalt(II), copper(II) and zinc(II) coordination compounds with 2-substituted benzimidazoles. J Inorg Biochem. 2009 Sep;103(9):1204-13. [Content Brief]
Keywords
