511-81-9
Chemical Structure
Machaeric acid
- CAS No.: 511-81-9
- Formula:C30H46O4
- Molecular Weight:470.68
InChIKey: YFBQOFTUFLWOHF-JIRMRKEISA-N
SMILES: OC([C@]12[C@](CC(C)(C(C2)=O)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Biological Activity: Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells[1][2].
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Machaeric acid | Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells. | |||||||||||||||||||||
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- [1]. Huo Y, et al. Antinociceptive activity and chemical composition of constituents from Caragana microphylla seeds. Phytomedicine. 2007;14(2-3):143-146. [Content Brief]
- [2]. Tchoukoua A, et al. Triterpene saponins from the roots of Acacia senegal (L.) Willd. Fitoterapia. 2021;151:104859. [Content Brief]
Keywords
