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Cat. No.: HY-N17637

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Machaeric acid

Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells.

For research use only. We do not sell to patients.

CAS No.: 511-81-9
Formula: C₃₀H₄₆O₄
Molecular Weight:470.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Machaeric acid Chemical Structure

CAS No.: 511-81-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Machaeric acid (compound 1) (200 μM; 48 h) does not exhibit significant cytotoxicity against H4IIE rat hepatoma cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[2]

Cell Line:

H4IIE rat hepatoma cells
Concentration:

200 μM
Incubation Time:

48 h
Result:

Was not significantly cytotoxic to H4IIE rat hepatoma cells at 200 μM.

Chemical Information

CAS No. 511-81-9
Molecular Weight 470.68
Formula C₃₀H₄₆O₄
SMILES

OC([C@]12[C@](CC(C)(C(C2)=O)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Structure Classification
- Terpenoids
- Pentacyclic Triterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huo Y, et al. Antinociceptive activity and chemical composition of constituents from Caragana microphylla seeds. Phytomedicine. 2007;14(2-3):143-146. [Content Brief]

[2]. Tchoukoua A, et al. Triterpene saponins from the roots of Acacia senegal (L.) Willd. Fitoterapia. 2021;151:104859. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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