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  3. Drug Intermediate
  4. Machaeric acid

Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells.

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Machaeric acid

Machaeric acid Chemical Structure

CAS No. : 511-81-9

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Machaeric acid Related Antibodies

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Description

Machaeric acid is a triterpenoid and triterpene sapogenin, which serves as the aglycone of Senegaloside A; it can be isolated from the seeds of Caragana microphylla Lam. and Acacia senegal(Mimosaceae). Machaeric acid exhibits remarkable biosafety, and even at concentrations as high as 200 μM, it does not induce cytotoxicity or reduce the viability of H4IIE rat hepatoma cells[1][2].

In Vitro

Machaeric acid (compound 1) (200 μM; 48 h) does not exhibit significant cytotoxicity against H4IIE rat hepatoma cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Machaeric acid Related Antibodies

Cell Viability Assay[2]

Cell Line: H4IIE rat hepatoma cells
Concentration: 200 μM
Incubation Time: 48 h
Result: Was not significantly cytotoxic to H4IIE rat hepatoma cells at 200 μM.
Molecular Weight

470.68

Formula

C30H46O4
CAS No.
SMILES

OC([C@]12[C@](CC(C)(C(C2)=O)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Machaeric acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Machaeric acid511-81-9Drug IntermediateDrug IintermediateAcacia senegalCaragana microphylla Lam.antinociceptive activitysenegaloside AH4IIE rat hepatoma cellstriterpenoid sapogenintriterpeneInhibitorinhibitorinhibit

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