51135-38-7
51135-38-7
Chemical Structure
7-Benzoyloxindole
- CAS No.: 51135-38-7
- Formula:C15H11NO2
- Molecular Weight:237.26
IUPAC Name: 7-benzoylindolin-2-one
InChIKey: APGQYYFHBPQPTL-UHFFFAOYSA-N
SMILES: O=C(C=1C=CC=CC1)C2=CC=CC3=C2NC(=O)C3
Biological Activity: 7-Benzoyloxindole (Compound 4a) is a tubulin destabilizer. 7-Benzoyloxindole disrupts the structure of microtubulin, thereby inhibiting the growth of tumor cells. 7-Benzoyloxindole can be used in the research of gastric cancer and lung cancer[1].
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7-Benzoyloxindole | 7-Benzoyloxindole (Compound 4a) is a tubulin destabilizer. 7-Benzoyloxindole disrupts the structure of microtubulin, thereby inhibiting the growth of tumor cells. 7-Benzoyloxindole can be used in the research of gastric cancer and lung cancer. | |||||||||||||||||||||
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References
- [1]. Chen J, Ye L, Su W. Palladium-catalyzed direct addition of arylboronic acids to 2-aminobenzonitrile derivatives: synthesis, biological evaluation and in silico analysis of 2-aminobenzophenones, 7-benzoyl-2-oxoindolines, and 7-benzoylindoles. Org Biomol Chem. 2014 Nov 7;12(41):8204-11. [Content Brief]
Keywords
