54230-76-1
54230-76-1
Chemical Structure
DNA-GAG
- CAS No.: 54230-76-1
- Formula:C30H37N15O15P2
- Molecular Weight:909.65
InChIKey: NYOIQXJPPQRLTD-SCFCQAABSA-N
SMILES: O=C1C(N=CN2[C@H]3C[C@H](OP(OC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)C[C@@H]4OP(OC[C@H]7O[C@@H](N(C=N8)C9=C8C(NC(N)=N9)=O)C[C@@H]7O)(O)=O)(O)=O)[C@@H](CO)O3)=C2N=C(N)N1
Biological Activity: DNA-GAG is a slow substrate for Ricin toxin A-chain (RTA). RTA depurinates a single adenylate on a GAGA stem-loop region of eukaryotic 28S RNA, making it a potent toxin[1].
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DNA-GAG | DNA-GAG is a slow substrate for Ricin toxin A-chain (RTA). RTA depurinates a single adenylate on a GAGA stem-loop region of eukaryotic 28S RNA, making it a potent toxin. | |||||||||||||||||||||
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References
Keywords
