612514-42-8
612514-42-8
Chemical Structure
VU0152099
- CAS No.: 612514-42-8
- Formula:C18H17N3O3S
- Molecular Weight:355.41
IUPAC Name: 3-amino-N-(benzo[d][1,3]dioxol-5-ylmethyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
InChIKey: AZOGCTMOKNTHIU-UHFFFAOYSA-N
SMILES: O=C(C1=C(N)C2=C(C)C=C(C)N=C2S1)NCC3=CC=C(OCO4)C4=C3
Biological Activity: VU0152099 is a potent, selective and brain-penetrant mAChR M4 positive allosteric modulator with an EC50 of 0.4 µM for rat M4 receptor. VU0152099 is inactive for other mAChR subtypes or other GPCRs. VU0152099 has no agonist activity but potentiated responses of M4 to acetylcholine[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VU0152099 | 98.39% | VU0152099 is a potent, selective and brain-penetrant mAChR M4 positive allosteric modulator with an EC50 of 0.4 µM for rat M4 receptor. VU0152099 is inactive for other mAChR subtypes or other GPCRs. VU0152099 has no agonist activity but potentiated responses of M4 to acetylcholine. | ||||||||||||||||||||
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References
Keywords
