637030-43-4
637030-43-4
Chemical Structure
H-Hyp-Leu-OH
- CAS No.: 637030-43-4
- Formula:C11H20N2O4
- Molecular Weight:244.29
InChIKey: LQFJGLSIESIIOM-VGMNWLOBSA-N
SMILES: CC(C)C[C@@H](C(O)=O)NC([C@H]1NC[C@@H](C1)O)=O
Biological Activity: H-Hyp-Leu-OH is a linear dipeptide of hydroxyproline-leucine with anti-inflammatory and antioxidant activities. H-Hyp-Leu-OH inhibits NO, IL-1β, IL-6, and TNF-α in macrophages, and upregulates IL-10. H-Hyp-Leu-OH extends lifespan, improves exercise capacity, reduces ROS and MDA, and increases SOD, CAT, and GSH-Px. H-Hyp-Leu-OH can be used for epithelial ovarian cancer and antioxidant-related research[1][2].
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H-Hyp-Leu-OH | H-Hyp-Leu-OH is a linear dipeptide of hydroxyproline-leucine with anti-inflammatory and antioxidant activities. H-Hyp-Leu-OH inhibits NO, IL-1β, IL-6, and TNF-α in macrophages, and upregulates IL-10. H-Hyp-Leu-OH extends lifespan, improves exercise capacity, reduces ROS and MDA, and increases SOD, CAT, and GSH-Px. H-Hyp-Leu-OH can be used for epithelial ovarian cancer and antioxidant-related research. | |||||||||||||||||||||
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References
- [1]. Liu L, et al. Structural basis for the anti-aging effects of hydroxyproline-BCAA dipeptides: An integrated computational and experimental approach. Food research international (Ottawa, Ont.). 2026 Jan 31;224:117962.
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[2]. Lu X, et al. Selection of small plasma peptides for the auxiliary diagnosis and prognosis of epithelial ovarian cancer by using UPLC/MS-based nontargeted and targeted analyses. International Journal of Cancer, 2019, 144(8): 2033-2042.
