649551-06-4
649551-06-4
Chemical Structure
JNJ-17156516
- CAS No.: 649551-06-4
- Formula:C26H22Cl2N2O3
- Molecular Weight:481.37
IUPAC Name: (S)-3-(5-(3,4-dichlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl)-2-(m-tolyl)propanoic acid
InChIKey: UZCIUKFEIOCAOC-QFIPXVFZSA-N
SMILES: O=C([C@@H](CC1=NN(C(C2=CC=C(C(Cl)=C2)Cl)=C1)C3=CC=C(C=C3)OC)C4=CC=CC(C)=C4)O
Biological Activity: JNJ-17156516 is an orally active, potent, and selective cholecystokinin (CCK)1-receptor antagonist[1].
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JNJ-17156516 | JNJ-17156516 is an orally active, potent, and selective cholecystokinin (CCK)1-receptor antagonist. | |||||||||||||||||||||
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References
- [1]. Morton MF, et al. 3-[5-(3,4-Dichloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-m-tolyl-propionate (JNJ-17156516), a novel, potent, and selective cholecystokinin 1 receptor antagonist: in vitro and in vivo pharmacological comparison with dexloxiglumide. J Pharmacol Exp Ther. 2007;323(2):562-569. IF: 3.5 Q2 B2 [Content Brief]
