66163-76-6
66163-76-6
Chemical Structure
3-Hydroxyterphenyllin
Synonym(s): NSC 299113
- CAS No.: 66163-76-6
- Formula:C20H18O6
- Molecular Weight:354.35
IUPAC Name: 3',6'-dimethoxy-[1,1':4',1''-terphenyl]-2',3,4,4''-tetraol
InChIKey: YLSPFNUVVOKJDF-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=CC(OC)=C(C3=CC=C(C(O)=C3)O)C(O)=C2OC)C=C1
Biological Activity: 3-Hydroxyterphenyllin is a metabolite of Aspergillus candidus.3-Hydroxyterphenyllin suppresses proliferation and causes cytotoxicity against A2780/CP70 and OVCAR-3 cells. 3-Hydroxyterphenyllin induces S phase arrest and apoptosis. 3-Hydroxyterphenyllin has the potential for the research of ovarian cancer[1][2].
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3-Hydroxyterphenyllin | 3-Hydroxyterphenyllin is a metabolite of Aspergillus candidus.3-Hydroxyterphenyllin suppresses proliferation and causes cytotoxicity against A2780/CP70 and OVCAR-3 cells. 3-Hydroxyterphenyllin induces S phase arrest and apoptosis. 3-Hydroxyterphenyllin has the potential for the research of ovarian cancer. | |||||||||||||||||||||
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References
- [1]. Kurobane I, et al. 3-Hydroxyterphenyllin, a new metabolite of Aspergillus candidus. Structure elucidation by H and C nuclear magnetic resonance spectroscopy. J Antibiot (Tokyo). 1979;32(6):559-564. [Content Brief]
- [2]. Wang Y, et al. 3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells. Int J Oncol. 2017;50(4):1392-1402. [Content Brief]
