670220-93-6
670220-93-6
Chemical Structure
Crenolanib benzenesulfonate
Synonym(s): CP 868596-26
- CAS No.: 670220-93-6
- Formula:C32H35N5O5S
- Molecular Weight:601.72
IUPAC Name: 1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine benzenesulfonate
InChIKey: ARQUTWAXTHJROR-UHFFFAOYSA-N
SMILES: NC1CCN(C2=CC=CC3=C2N=C(N4C5=CC=C(C=C5N=C4)OCC6(COC6)C)C=C3)CC1.O=S(C7=CC=CC=C7)(O)=O
Biological Activity: Crenolanib benzenesulfonate is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases FLT3 and PDGFRα/β with Kds of 0.74 nM and 2.1 nM/3.2 nM, respectively.
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Crenolanib benzenesulfonate | 99.45% | Crenolanib benzenesulfonate is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases FLT3 and PDGFRα/β with Kds of 0.74 nM and 2.1 nM/3.2 nM, respectively. | ||||||||||||||||||||
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Keywords
