68813-55-8
68813-55-8
Chemical Structure
Oxantel pamoate
Synonym(s): Oxantel embonate
- CAS No.: 68813-55-8
- Formula:C36H32N2O7
- Molecular Weight:604.65
IUPAC Name: (E)-3-(2-(1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)vinyl)phenol 4,4'-methylenebis(3-hydroxy-2-naphthoate)
InChIKey: CCOAINFUFGBHBA-UETGHTDLSA-N
SMILES: O=C(C1=C(O)C(CC2=C3C=CC=CC3=CC(C(O)=O)=C2O)=C4C=CC=CC4=C1)O.OC5=CC=CC(/C=C/C6=NCCCN6C)=C5
Biological Activity: Oxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Oxantel pamoate | 99.90% | Oxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM). | ||||||||||||||||||||
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Oxantel pamoate (Standard) | ≥98% | Oxantel pamoate (Standard) (Oxantel embonate (Standard)) is the analytical standard of Oxantel pamoate (HY-B1344). This product is intended for research and analytical applications. Oxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM). | ||||||||||||||||||||
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References
- [1]. Keiser J, et al. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis. 2013;7(3):e2119. [Content Brief]
- [2]. Dashper S, et al. Oxantel disrupts polymicrobial biofilm development of periodontal pathogens. Antimicrob Agents Chemother. 2014;58(1):378-85. [Content Brief]
