692774-37-1
692774-37-1
Chemical Structure
BFC1108
- CAS No.: 692774-37-1
- Formula:C23H21ClN2O4
- Molecular Weight:424.88
InChIKey: KSBAFMQAXIHVCL-UHFFFAOYSA-N
SMILES: CCOC1=CC=CC=C1NC(C2=CC(Cl)=CC=C2NC(C3=CC=C(OC)C=C3)=O)=O
Biological Activity: BFC1108 is a small molecule Bcl-2 functional converter. BFC1108 induces a conformational change in Bcl-2, resulting in the exposure of its BH3 domain both in vitro and in vivo. BFC1108 effectively induces apoptosis in Bcl-2 expressing cancers.[1].
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BFC1108 | 98.11% | BFC1108 is a small molecule Bcl-2 functional converter. BFC1108 induces a conformational change in Bcl-2, resulting in the exposure of its BH3 domain both in vitro and in vivo. BFC1108 effectively induces apoptosis in Bcl-2 expressing cancers.. | ||||||||||||||||||||
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References
Keywords
