70630-17-0
Chemical Structure
Metalaxyl-M
Synonym(s): (R)-Metalaxyl
- CAS No.: 70630-17-0
- Formula:C15H21NO4
- Molecular Weight:279.33
IUPAC Name: methyl N-(2,6-dimethylphenyl)-N-(2-methoxyacetyl)-D-alaninate
InChIKey: ZQEIXNIJLIKNTD-GFCCVEGCSA-N
SMILES: C[C@H](C(OC)=O)N(C1=C(C)C=CC=C1C)C(COC)=O
Biological Activity: Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Metalaxyl-M | 98.09% | Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Metalaxyl-M (Standard) | 97.40% | Metalaxyl-M ((R)-Metalaxyl) (Standard) is the analytical standard of Metalaxyl-M (HY-B0843A). This product is intended for research and analytical applications. Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Metalaxyl-M-d6 | 99.9% | Metalaxyl-M-d6 ((R)-Metalaxyl-d6) is the deuterium labeled Metalaxyl-M (HY-B0843A). Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Yinjun Zhang, et al. Bio-preparation of (R)-DMPM using whole cells of Pseudochrobactrum asaccharolyticum WZZ003 and its application on kilogram-scale synthesis of fungicide (R)-metalaxyl. Biotechnol Prog [Content Brief]
- [2]. OuYang MN, et al. The different toxic effects of metalaxyl and metalaxyl-M on Tubifex tubifex. Ecotoxicol Environ Saf. 2021 Jan 15;208:111587. [Content Brief]
- [3]. Zhang P, et al. Identifying Metabolic Perturbations and Toxic Effects of Rac-Metalaxyl and Metalaxyl-M in Mice Using Integrative NMR and UPLC-MS/MS Based Metabolomics. Int J Mol Sci. 2019 Nov 1;20(21):5457. [Content Brief]